VPS51

Across TCGA patient cohorts, VPS51 protein abundance is significantly associated with the RNA expression of many other genes, with 7,748 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VPS51-associated genes across cancer lineages are PMPCB, ALDH6A1, and SNAI1. Each is linked with VPS51 in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS51-to-partner and partner-to-VPS51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS51 versus PMPCB in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS51→partner) and Y-score (partner→VPS51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PMPCB →	+0.390	+0.218	.004	.001	3	4
LUAD	ALDH6A1 →	+0.776	+0.126	<.001	<.001	3	4
PDAC	SNAI1 →	-0.609	-0.151	<.001	<.001	3	4
LUAD	AHCYL2 →	+0.849	+0.093	<.001	.002	3	4
LUAD	RPH3AL →	+0.722	+0.141	<.001	<.001	3	4
BRCA	FIS1 →	+0.458	+0.153	.006	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,748 associations by consensus.

VPS51 vs PMPCB — OV

Explore this scatter interactively →