VPS37A

Across TCGA cell cohorts, VPS37A protein abundance is significantly associated with the RNA expression of many other genes, with 1,874 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS37A-associated genes across cancer lineages are DNAI4, HOXB3, and MTA1. Each is linked with VPS37A in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS37A-to-partner and partner-to-VPS37A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS37A versus DNAI4 in LUNG_NSCLC_LUAD, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37A→partner) and Y-score (partner→VPS37A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DNAI4 →	-0.857	-1.327	.005	.008	3	4
UPPER_AERODIGESTIVE_TRACT	HOXB3 →	-2.112	-3.170	.009	.005	3	3
UPPER_AERODIGESTIVE_TRACT	MTA1 →	-0.940	-1.967	.006	.007	3	3
UPPER_AERODIGESTIVE_TRACT	CENATAC →	-1.881	-1.989	<.001	.006	3	3
UPPER_AERODIGESTIVE_TRACT	PATE4 →	-0.104	-2.518	.001	<.001	3	3
BLOOD_Lymphoma	NCKIPSD →	-0.596	-1.006	.007	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,874 associations by consensus.

VPS37A vs DNAI4 — LUNG_NSCLC_LUAD

Explore this scatter interactively →