VPS26C

Across TCGA patient cohorts, VPS26C protein abundance is significantly associated with the RNA expression of many other genes, with 12,477 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS26C-associated genes across cancer lineages are MAN1C1, TMEM273, and MAGI2-AS3. Each is linked with VPS26C in more than 6 cancer types. Because this analysis shows association rather than direction, both VPS26C-to-partner and partner-to-VPS26C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS26C versus MAN1C1 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS26C→partner) and Y-score (partner→VPS26C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAN1C1 →	+0.878	+0.220	<.001	<.001	3	7
GBM	TMEM273 →	+0.859	+0.242	<.001	.002	3	6
BRCA	MAGI2-AS3 →	+0.590	+0.213	.001	<.001	3	6
BRCA	ARHGEF6 →	+0.684	+0.157	<.001	<.001	3	5
LSCC	FLI1 →	+0.745	+0.284	<.001	<.001	3	5
LSCC	ABI3BP →	+0.939	+0.277	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,477 associations by consensus.

VPS26C vs MAN1C1 — GBM

Explore this scatter interactively →