VPS25

Across TCGA patient cohorts, VPS25 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,843 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS25-associated proteins across cancer lineages are MCM2, MCM3, and MCM4. Each is linked with VPS25 in more than 5 cancer types. Because this analysis shows association rather than direction, both VPS25-to-partner and partner-to-VPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS25 versus MCM2 in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS25→partner) and Y-score (partner→VPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MCM2 →	+0.572	+0.412	<.001	<.001	3	6
LUAD	MCM3 →	+0.645	+0.336	<.001	<.001	3	6
LUAD	MCM4 →	+0.661	+0.358	<.001	<.001	3	6
GBM	MCM5 →	+0.761	+0.286	<.001	<.001	3	6
LSCC	MCM7 →	+0.599	+0.456	<.001	<.001	3	6
LSCC	THOC7 →	+0.318	+0.544	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,843 associations by consensus.

VPS25 vs MCM2 — LSCC

Explore this scatter interactively →