VPS13B-DT

Across TCGA patient cohorts, VPS13B-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 14,323 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS13B-DT-associated proteins across cancer lineages are RBM12B, RBBP4, and NELFA. Each is linked with VPS13B-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS13B-DT-to-partner and partner-to-VPS13B-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS13B-DT versus RBM12B in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS13B-DT→partner) and Y-score (partner→VPS13B-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBM12B →	+0.238	+0.327	<.001	<.001	3	5
LSCC	RBBP4 →	+0.297	+0.337	<.001	<.001	3	5
LSCC	NELFA →	+0.281	+0.488	<.001	<.001	3	5
LSCC	PIK3C2A_S259 →	-0.511	-0.391	.001	.001	3	5
GBM	RABGGTA →	-0.203	-0.329	.002	.006	3	4
LSCC	NELFCD →	+0.307	+0.429	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,323 associations by consensus.

VPS13B-DT vs RBM12B — LSCC

Explore this scatter interactively →