Across TCGA patient cohorts, VPS13A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,048 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS13A-associated proteins across cancer lineages are ANP32B, BSPRY, and CALR. Each is linked with VPS13A in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS13A-to-partner and partner-to-VPS13A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS13A→partner) and Y-score (partner→VPS13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANP32B →	+0.305	+0.502	<.001	<.001	3	4
UCEC	BSPRY →	+0.609	+0.385	.001	.008	3	4
CCRCC	CALR →	-0.283	-0.457	.002	.005	3	4
LSCC	ILKAP →	+0.279	+0.458	.004	.003	3	4
PDAC	PTBP3 →	+0.300	+0.352	<.001	.003	3	4
BRCA	RABGAP1 →	+0.243	+0.722	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,048 associations by consensus.

Exploration

VPS13A survival (RNA) · tumor vs normal (RNA) · all VPS13A data types