VNN1

Across TCGA patient cohorts, VNN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,531 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VNN1-associated proteins across cancer lineages are ACAP1_T739, ADNP, and TNFAIP8. Each is linked with VNN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VNN1-to-partner and partner-to-VNN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VNN1 versus ACAP1_T739 in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VNN1→partner) and Y-score (partner→VNN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACAP1_T739 →	+0.948	+0.698	<.001	<.001	3	7
OV	ADNP →	-0.372	-1.724	<.001	<.001	3	7
GBM	TNFAIP8 →	+0.729	+0.695	<.001	<.001	3	7
BRCA	LPXN →	+0.572	+0.940	<.001	<.001	3	6
GBM	LRRFIP1 →	+0.342	+0.578	<.001	<.001	3	6
LSCC	RCSD1_S179 →	+0.674	+0.881	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,531 associations by consensus.

VNN1 vs ACAP1_T739 — GBM

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