VNN1

Across TCGA patient cohorts, VNN1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,972 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VNN1-associated genes across cancer lineages are CXCL8, VNN2, and CCNG1P1. Each is linked with VNN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both VNN1-to-partner and partner-to-VNN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VNN1 versus CXCL8 in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VNN1→partner) and Y-score (partner→VNN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXCL8 →	+1.983	+0.601	.001	.002	3	5
CCRCC	VNN2 →	+0.869	+0.694	<.001	<.001	3	5
UCEC	CCNG1P1 →	+1.187	+0.902	<.001	<.001	3	5
OV	LYVE1 →	+1.561	+0.829	.002	.008	3	4
LSCC	CSF3 →	+1.033	+0.607	<.001	<.001	3	4
LSCC	CSF3R →	+0.933	+0.630	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,972 associations by consensus.

VNN1 vs CXCL8 — GBM

Explore this scatter interactively →