VNN1

Across TCGA cell cohorts, VNN1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VNN1-associated genes across cancer lineages are LRTM1, CABS1, and OR5G3. Each is linked with VNN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VNN1-to-partner and partner-to-VNN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRTM1 grouped by VNN1-low versus VNN1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VNN1→partner) and Y-score (partner→VNN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LRTM1 →	+0.052	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	CABS1 →	+0.073	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR5G3 →	+0.024	+4.867	.008	.009	3	1
BLOOD_Lymphoma	DGKK →	+0.016	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

LRTM1 by VNN1 expression — BLOOD_Lymphoma

Explore this box plot interactively →