VN1R4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VN1R4 mutation is significantly associated with the RNA expression of many other genes, with 964 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VN1R4-associated genes across cancer lineages are LINC01318, TSEN34, and MIR3666. Each is linked with VN1R4 in more than 2 cancer types. Because this analysis shows association rather than direction, both VN1R4-to-partner and partner-to-VN1R4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R4→partner) and Y-score (partner→VN1R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCLINC01318 →+0.156+5.368<.001.00533
SKCMTSEN34 →+0.418+2.443<.001.00133
BRCAMIR3666 →+0.478+6.268<.001.00132
UCECFDXR →+0.652+3.329.007.00532
UCECGHITM →+0.772+3.513<.001.00232
HNSCOR2T34 →+0.079+5.505<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 964 associations by consensus.

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