Q-omics provides the consensus-scored MIR3666 profile across patient tissues and cancer cell-line models. MIR3666 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MIR3666 is differentially expressed in 2, with the highest sampling consensus in KIRP. Additionally, MIR3666 RNA expression shows 8,335 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight KIRC, KIRP, and LSCC as cancer lineages where MIR3666 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR3666 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR3666 survival associations across molecular data types. MIR3666 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR3666 RNA expression–survival associations across cancer types. High MIR3666 expression shows unfavorable associations in KIRC, LIHC, LAML and LGG, but favorable associations in LUAD and SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MIR3666 RNA expression.
This table summarizes MIR3666 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for MIR3666. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR3666 shows higher tumor expression in KIRP and LUAD. The KIRP box plot shows higher MIR3666 RNA expression in tumor versus normal tissue (log2 FC = +0.190, t-test p = .005).
This table shows molecular features associated with MIR3666 in patient tissues and cancer cell lines. In patient samples, MIR3666 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
