Across TCGA pan-cancer cohorts, MIR3666 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR3666’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MIR3666 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3666 is over-expressed in tumor.
KIRP and LUAD are the cancer types where MIR3666 tumor–normal differential expression is most reproducible.