VIL1

Across TCGA cell cohorts, VIL1 mutation is significantly associated with the mutation status of many other genes, with 2,146 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VIL1-associated genes across cancer lineages are DOCK6, COX10, and HIP1. Each is linked with VIL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both VIL1-to-partner and partner-to-VIL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DOCK6 grouped by VIL1-low versus VIL1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIL1→partner) and Y-score (partner→VIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DOCK6 →	+4.392	+4.392	.009	.009	1	4
SKIN	COX10 →	+5.392	+4.824	.004	.004	1	3
SKIN	HIP1 →	+4.392	+4.392	.009	.009	1	3
SKIN	CDH8 →	+2.655	+4.113	.009	.009	1	3
SKIN	STARD9 →	+2.807	+4.247	.007	.007	1	3
SKIN	U2SURP →	+5.392	+4.824	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,146 associations by consensus.

DOCK6 by VIL1 expression — SKIN

Explore this box plot interactively →