VEGFD

Across TCGA patient cohorts, VEGFD protein abundance is significantly associated with the RNA expression of many other genes, with 6,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VEGFD-associated genes across cancer lineages are MFNG, LGALS2, and GRAP2. Each is linked with VEGFD in more than 1 cancer types. Because this analysis shows association rather than direction, both VEGFD-to-partner and partner-to-VEGFD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VEGFD versus MFNG in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFD→partner) and Y-score (partner→VEGFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MFNG →	+0.536	+0.546	<.001	<.001	3	2
LSCC	LGALS2 →	+0.676	+0.455	.002	.004	3	2
LSCC	GRAP2 →	+0.493	+0.416	.002	.002	3	2
LUAD	CTSG →	+0.791	+0.511	.001	.001	3	2
LUAD	CDKN3 →	-0.861	-0.520	.001	.001	3	2
LSCC	PSMB5 →	-0.403	-0.595	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,408 associations by consensus.

VEGFD vs MFNG — LSCC

Explore this scatter interactively →