VEGFD

Across TCGA patient cohorts, VEGFD mutation is significantly associated with the RNA expression of many other genes, with 3,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VEGFD-associated genes across cancer lineages are MIR655, PSAT1P4, and SURF6P1. Each is linked with VEGFD in more than 2 cancer types. Because this analysis shows association rather than direction, both VEGFD-to-partner and partner-to-VEGFD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR655 grouped by VEGFD-low versus VEGFD-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFD→partner) and Y-score (partner→VEGFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR655 →	+0.547	+7.930	<.001	.008	3	3
BRCA	PSAT1P4 →	+0.678	+6.231	<.001	<.001	3	3
BLCA	SURF6P1 →	+0.105	+5.685	<.001	.003	3	3
LUAD	RNU6-217P →	+0.198	+7.930	<.001	.008	3	2
STAD	RN7SL544P →	+0.185	+5.772	<.001	<.001	3	2
UCEC	SCMH1 →	+0.351	+2.732	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,695 associations by consensus.

MIR655 by VEGFD expression — LUAD

Explore this box plot interactively →