VEGFC

Across TCGA cell cohorts, VEGFC RNA expression is significantly associated with the go_rna of many other GO terms, with 5,295 significant associations in total. BONE shows the largest number of these associations.

The most reproducible VEGFC-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of cell-substrate junction organization, and Negative regulation of fatty acid transport. Each is linked with VEGFC in more than 11 cancer types. Because this analysis shows association rather than direction, both VEGFC-to-partner and partner-to-VEGFC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by VEGFC-low versus VEGFC-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFC→partner) and Y-score (partner→VEGFC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.188	+3.460	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate junction organization →	+0.154	+3.456	<.001	<.001	3	11
BONE	Negative regulation of fatty acid transport →	+0.173	+2.886	<.001	.001	3	10
BONE	Establishment of epithelial cell apical/basal polarity →	+0.157	+3.586	<.001	<.001	3	10
BREAST	Lactate metabolic process →	+0.148	+1.443	.003	.005	3	10
SOFT_TISSUE	Amino acid catabolic process →	-0.066	-2.936	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,295 associations by consensus.

Positive regulation of focal adhesion assembly by VEGFC expression — BONE

Explore this box plot interactively →