VDAC3

Across TCGA patient cohorts, VDAC3 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VDAC3-associated genes across cancer lineages are CLP, DC, and Hepatocytes. Each is linked with VDAC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both VDAC3-to-partner and partner-to-VDAC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by VDAC3-low versus VDAC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC3→partner) and Y-score (partner→VDAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.079	-3.279	.016	.011	3	1
UCEC	DC →	+0.025	+3.386	.017	.004	3	1
UCEC	Hepatocytes →	+0.016	+2.577	.003	.016	3	1
UCEC	pDC →	+0.068	+2.180	.007	.036	3	1
UCEC	Myocytes →	+0.042	+2.212	.012	.034	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CLP by VDAC3 expression — UCEC

Explore this box plot interactively →