VDAC3

Across TCGA cell cohorts, VDAC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,258 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VDAC3-associated GO terms across cancer lineages are Interkinetic nuclear migration, Clathrin-coated vesicle cargo loading, and Clathrin-coated vesicle cargo loading, AP-3-mediated. Each is linked with VDAC3 in more than 13 cancer types. Because this analysis shows association rather than direction, both VDAC3-to-partner and partner-to-VDAC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interkinetic nuclear migration grouped by VDAC3-low versus VDAC3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC3→partner) and Y-score (partner→VDAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Interkinetic nuclear migration →	+0.118	+0.974	<.001	.004	3	14
PANCREAS	Clathrin-coated vesicle cargo loading →	+0.118	+0.765	<.001	<.001	3	13
PANCREAS	Clathrin-coated vesicle cargo loading, AP-3-mediated →	+0.118	+0.765	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.114	+1.050	<.001	<.001	3	12
LIVER	Negative regulation of heterochromatin organization →	+0.123	+0.956	.001	.007	3	11
LIVER	Negative regulation of heterochromatin formation →	+0.123	+0.956	.001	.007	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,258 associations by consensus.

Interkinetic nuclear migration by VDAC3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →