VDAC2P2

Across TCGA patient cohorts, VDAC2P2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,285 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VDAC2P2-associated proteins across cancer lineages are RCSD1_S179, SASH3, and SH2D1A. Each is linked with VDAC2P2 in more than 5 cancer types. Because this analysis shows association rather than direction, both VDAC2P2-to-partner and partner-to-VDAC2P2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VDAC2P2 versus RCSD1_S179 in PDAC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC2P2→partner) and Y-score (partner→VDAC2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RCSD1_S179 →	+0.629	+0.424	<.001	.003	3	6
UCEC	SASH3 →	+0.392	+0.625	.007	.001	3	6
LSCC	SH2D1A →	+0.675	+0.614	<.001	<.001	3	6
LSCC	SH3KBP1 →	+0.442	+0.484	<.001	<.001	3	6
HNSC	WAS →	+0.382	+0.439	<.001	<.001	3	6
PDAC	CARMIL2_S1381 →	+1.104	+0.698	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,285 associations by consensus.

VDAC2P2 vs RCSD1_S179 — PDAC

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