VDAC2P2

Across TCGA pan-cancer cohorts, VDAC2P2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated VDAC2P2 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher VDAC2P2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated VDAC2P2 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

UCS, UVM, and COAD are the cancer types where VDAC2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	III,IV	0.753	0.216	.006	70	view →
UVM	OS	Tertile	All	0.326	0.758	.001	48	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
LUSC	DFS	Tertile	II,III,IV	0.601	0.750	.005	21	view →
ESCA	DFS	Quartile	III,IV	0.614	0.309	.003	21	view →
ACC	DFS	Tertile	III,IV	0.117	0.522	.002	21	view →
LAML	DFS	Tertile	All	0.433	0.653	.007	18	view →
LUAD	DFS	Median	IV	0.301	0.753	.006	16	view →
SKCM	OS	Quartile	II,III,IV	0.495	0.283	.013	12	view →
MESO	OS	Median	IV	0.307	0.692	.021	9	view →
OV	OS	Quartile	II,III,IV	0.379	0.292	.038	8	view →
THCA	OS	Tertile	All	0.976	0.998	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

VDAC2P2–UCS (OS)

Open the UCS breakdown →