VDAC1P9

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VDAC1P9 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,795 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VDAC1P9-associated proteins across cancer lineages are GRB2, VAV1, and PSMB6. Each is linked with VDAC1P9 in more than 3 cancer types. Because this analysis shows association rather than direction, both VDAC1P9-to-partner and partner-to-VDAC1P9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VDAC1P9 versus GRB2 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1P9→partner) and Y-score (partner→VDAC1P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCGRB2 →+0.251+0.318<.001<.00134
HNSCVAV1 →+0.385+0.239<.001.00333
HNSCPSMB6 →-0.346-0.216<.001.00433
LSCCTRAF3IP3 →+0.499+0.253<.001<.00133
HNSCSEMA4A →+0.443+0.220<.001.00233
LSCCTAGAP_S59 →+1.014+0.267<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,795 associations by consensus.

VDAC1P9 vs GRB2 — LSCC

Per-sample scatter of VDAC1P9 vs GRB2 in LSCC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration