VDAC1P9

Across TCGA pan-cancer cohorts, VDAC1P9 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of VDAC1P9’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where VDAC1P9 RNA is repressed in tumor relative to normal tissue. In most cancer types VDAC1P9 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, HNSC, and KIRC are the cancer types where VDAC1P9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VDAC1P9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.033	<.001	5	view →
HNSC	All	II,III,IV	+0.013	.041	2	view →
KIRC	All	All	+0.009	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

VDAC1P9–THCA

Open the THCA breakdown →