VDAC1P9

Across TCGA pan-cancer cohorts, VDAC1P9 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated VDAC1P9 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher VDAC1P9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VDAC1P9 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

KIRC, ACC, and COAD are the cancer types where VDAC1P9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.428	0.679	<.001	108	view →
ACC	OS	Tertile	All	0.128	0.812	<.001	90	view →
COAD	OS	Tertile	II,III,IV	0.487	0.864	<.001	72	view →
OV	OS	Tertile	IV	0.350	0.804	.007	36	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
LGG	DFS	Tertile	All	0.412	0.742	.008	27	view →
KICH	DFS	Tertile	All	0.121	0.867	.023	24	view →
READ	DFS	Tertile	III,IV	0.174	0.747	.005	21	view →
ESCA	DFS	Median	III,IV	0.442	0.238	.009	20	view →
BLCA	OS	Tertile	IV	0.147	0.601	.001	18	view →
THYM	DFS	Tertile	II,III,IV	0.252	0.808	.015	15	view →
SARC	OS	Tertile	All	0.281	0.733	.035	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

VDAC1P9–KIRC (OS)

Open the KIRC breakdown →