VDAC1P9

Across TCGA patient cohorts, VDAC1P9 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,511 significant associations in total. STAD shows the largest number of these associations.

The most reproducible VDAC1P9-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Nucleoside phosphate biosynthetic process, and Nucleoside triphosphate metabolic process. Each is linked with VDAC1P9 in more than 13 cancer types. Because this analysis shows association rather than direction, both VDAC1P9-to-partner and partner-to-VDAC1P9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by VDAC1P9-low versus VDAC1P9-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1P9→partner) and Y-score (partner→VDAC1P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA metabolic process →	+0.073	+0.202	<.001	<.001	3	14
STAD	Nucleoside phosphate biosynthetic process →	+0.056	+0.190	<.001	<.001	3	13
STAD	Nucleoside triphosphate metabolic process →	+0.060	+0.181	<.001	<.001	3	13
ESCA	Regulation of viral process →	+0.058	+0.148	<.001	.001	3	13
STAD	Protein localization to mitochondrion →	+0.056	+0.186	<.001	<.001	3	13
ESCA	Regulation of DNA repair →	+0.068	+0.206	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,511 associations by consensus.

Positive regulation of DNA metabolic process by VDAC1P9 expression — ESCA

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