VDAC1P4

Across TCGA patient cohorts, VDAC1P4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,587 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VDAC1P4-associated proteins across cancer lineages are THOC2, TRIM21, and TRIM28_S697. Each is linked with VDAC1P4 in more than 5 cancer types. Because this analysis shows association rather than direction, both VDAC1P4-to-partner and partner-to-VDAC1P4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VDAC1P4 versus THOC2 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1P4→partner) and Y-score (partner→VDAC1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	THOC2 →	+0.281	+0.430	<.001	<.001	3	6
HNSC	TRIM21 →	-0.435	-0.491	.003	<.001	3	5
OV	TRIM28_S697 →	+0.738	+0.352	.002	.003	3	5
HNSC	POGK →	+0.456	+0.791	<.001	<.001	3	5
UCEC	POGZ →	+0.292	+0.744	<.001	<.001	3	5
LUAD	PRCC_S267 →	+0.425	+0.509	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,587 associations by consensus.

VDAC1P4 vs THOC2 — GBM

Explore this scatter interactively →