VDAC1P4

Across TCGA patient cohorts, VDAC1P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,312 significant associations in total. STAD shows the largest number of these associations.

The most reproducible VDAC1P4-associated GO terms across cancer lineages are Microtubule polymerization, Spindle organization, and Cytoplasmic microtubule organization. Each is linked with VDAC1P4 in more than 23 cancer types. Because this analysis shows association rather than direction, both VDAC1P4-to-partner and partner-to-VDAC1P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by VDAC1P4-low versus VDAC1P4-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1P4→partner) and Y-score (partner→VDAC1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Microtubule polymerization →	+0.044	+0.142	<.001	<.001	3	24
STAD	Spindle organization →	+0.056	+0.207	<.001	<.001	3	23
ESCA	Cytoplasmic microtubule organization →	+0.048	+0.190	<.001	<.001	3	23
STAD	Centrosome duplication →	+0.049	+0.182	<.001	<.001	3	23
STAD	Epigenetic regulation of gene expression →	+0.052	+0.213	<.001	<.001	3	22
STAD	Ribosomal large subunit biogenesis →	+0.060	+0.180	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,312 associations by consensus.

Microtubule polymerization by VDAC1P4 expression — ESCA

Explore this box plot interactively →