VDAC1P10

Across TCGA pan-cancer cohorts, VDAC1P10 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated VDAC1P10 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher VDAC1P10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VDAC1P10 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

STAD, KICH, and ACC are the cancer types where VDAC1P10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Quartile	II,III,IV	0.235	0.623	.002	61	view →
KICH	OS	Tertile	All	0.191	0.875	.001	36	view →
ACC	DFS	Tertile	III,IV	0.038	0.472	<.001	36	view →
PCPG	OS	Tertile	All	0.310	0.967	.003	27	view →
ESCA	DFS	Quartile	IV	0.826	0.262	.040	24	view →
SKCM	OS	Median	All	0.700	0.855	.001	21	view →
LUSC	OS	Tertile	II,III,IV	0.469	0.794	.011	21	view →
UCEC	OS	Tertile	IV	0.231	0.592	.036	18	view →
BLCA	OS	Tertile	IV	0.176	0.608	<.001	18	view →
DLBC	OS	Tertile	All	0.053	0.936	<.001	18	view →
LIHC	DFS	Tertile	III,IV	0.139	0.371	.023	18	view →
LGG	OS	Tertile	All	0.265	0.494	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

VDAC1P10–STAD (OS)

Open the STAD breakdown →