voltage dependent anion channel 1 pseudogene 10Genealiases: []
Q-omics provides the consensus-scored VDAC1P10 profile across patient tissues and cancer cell-line models. VDAC1P10 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, VDAC1P10 is differentially expressed in 2, with the highest sampling consensus in COAD. Additionally, VDAC1P10 RNA expression shows 5,167 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight STAD, and COAD as cancer lineages where VDAC1P10 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for VDAC1P10 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes VDAC1P10 survival associations across molecular data types. VDAC1P10 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible VDAC1P10 RNA expression–survival associations across cancer types. High VDAC1P10 expression shows unfavorable associations in STAD, ACC, KICH, PCPG and LUSC, but favorable associations in ESCA. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify STAD as the clearest survival context for VDAC1P10 RNA expression.
This table summarizes VDAC1P10 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for VDAC1P10. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. VDAC1P10 shows higher tumor expression in COAD and LUAD. The COAD box plot shows higher VDAC1P10 RNA expression in tumor versus normal tissue (log2 FC = +0.040, t-test p = .015).
This table shows molecular features associated with VDAC1P10 in patient tissues and cancer cell lines. In patient samples, VDAC1P10 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
