VAMP8

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VAMP8 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VAMP8-associated genes across cancer lineages are pDC. Each is linked with VAMP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both VAMP8-to-partner and partner-to-VAMP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by VAMP8-low versus VAMP8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP8→partner) and Y-score (partner→VAMP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECpDC →+0.111+2.818<.001.03711
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

pDC by VAMP8 expression — UCEC

Box plot of pDC in VAMP8-low vs VAMP8-high samples in UCEC.

Explore this box plot interactively →

Exploration