VAMP8

Across TCGA cell cohorts, VAMP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,716 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VAMP8-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Mucus secretion, and Autophagosome membrane docking. Each is linked with VAMP8 in more than 15 cancer types. Because this analysis shows association rather than direction, both VAMP8-to-partner and partner-to-VAMP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytotoxic T cell degranulation grouped by VAMP8-low versus VAMP8-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP8→partner) and Y-score (partner→VAMP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytotoxic T cell degranulation →	+0.354	+3.291	<.001	<.001	3	16
SOFT_TISSUE	Mucus secretion →	+1.418	+3.008	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Autophagosome membrane docking →	+0.203	+2.498	<.001	.001	3	14
LUNG_NSCLC_LUSC	Secretion by tissue →	+0.322	+3.407	.004	.002	2	13
URINARY_TRACT	Regulation of histamine secretion by mast cell →	+0.217	+3.203	<.001	.002	3	11
URINARY_TRACT	Positive regulation of histamine secretion by mast cell →	+0.217	+3.203	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,716 associations by consensus.

Cytotoxic T cell degranulation by VAMP8 expression — STOMACH

Explore this box plot interactively →