VAMP7

Across TCGA patient cohorts, VAMP7 protein abundance is significantly associated with the RNA expression of many other genes, with 15,543 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VAMP7-associated genes across cancer lineages are ATP6AP1, ZFYVE21, and TRIP11. Each is linked with VAMP7 in more than 5 cancer types. Because this analysis shows association rather than direction, both VAMP7-to-partner and partner-to-VAMP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAMP7 versus ATP6AP1 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP7→partner) and Y-score (partner→VAMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ATP6AP1 →	+0.888	+0.503	<.001	<.001	3	6
CCRCC	ZFYVE21 →	-0.564	-0.314	<.001	<.001	3	5
BRCA	TRIP11 →	-0.715	-0.444	<.001	<.001	3	5
CCRCC	DMAC2L →	-0.480	-0.290	<.001	<.001	3	5
BRCA	EAPP →	-0.512	-0.482	.002	<.001	3	5
LUAD	LAGE3 →	+0.603	+0.298	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,543 associations by consensus.

VAMP7 vs ATP6AP1 — OV

Explore this scatter interactively →