VAMP5

Across TCGA patient cohorts, VAMP5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,204 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VAMP5-associated genes across cancer lineages are GIMAP4, CXCL9, and WARS1. Each is linked with VAMP5 in more than 8 cancer types. Because this analysis shows association rather than direction, both VAMP5-to-partner and partner-to-VAMP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAMP5 versus GIMAP4 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP5→partner) and Y-score (partner→VAMP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GIMAP4 →	+0.974	+0.406	<.001	.001	3	9
BRCA	CXCL9 →	+2.124	+0.561	<.001	.004	3	9
LUAD	WARS1 →	+1.138	+0.561	<.001	<.001	3	9
OV	CCR5 →	+1.812	+0.694	<.001	<.001	3	9
OV	PRF1 →	+1.555	+0.658	<.001	<.001	3	9
UCEC	GIMAP5 →	+0.977	+0.738	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,204 associations by consensus.

VAMP5 vs GIMAP4 — GBM

Explore this scatter interactively →