VAMP5

Across TCGA cell cohorts, VAMP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,121 significant associations in total. BONE shows the largest number of these associations.

The most reproducible VAMP5-associated GO terms across cancer lineages are Protein localization to cell periphery, Barbed-end actin filament capping, and Protein localization to plasma membrane. Each is linked with VAMP5 in more than 11 cancer types. Because this analysis shows association rather than direction, both VAMP5-to-partner and partner-to-VAMP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cell periphery grouped by VAMP5-low versus VAMP5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP5→partner) and Y-score (partner→VAMP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein localization to cell periphery →	+0.072	+3.623	<.001	<.001	3	12
BONE	Barbed-end actin filament capping →	+0.260	+3.966	<.001	<.001	3	10
BONE	Protein localization to plasma membrane →	+0.086	+3.623	<.001	<.001	3	10
KIDNEY	Regulation of tolerance induction dependent upon immune response →	+1.398	+2.938	<.001	<.001	3	10
BONE	Protein localization to membrane →	+0.086	+3.367	<.001	<.001	3	10
BONE	Regulation of protein localization to membrane →	+0.087	+3.716	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,121 associations by consensus.

Protein localization to cell periphery by VAMP5 expression — BONE

Explore this box plot interactively →