Across TCGA patient cohorts, VAMP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,767 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VAMP2-associated proteins across cancer lineages are MYEF2, PAFAH1B1, and AGO1. Each is linked with VAMP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both VAMP2-to-partner and partner-to-VAMP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP2→partner) and Y-score (partner→VAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYEF2 →	+0.670	+0.767	<.001	<.001	3	5
GBM	PAFAH1B1 →	+0.305	+0.927	<.001	<.001	3	5
BRCA	AGO1 →	+0.311	+0.607	<.001	<.001	3	5
BRCA	GLOD4 →	+0.352	+0.591	<.001	<.001	3	5
BRCA	RABEP1 →	+0.530	+0.730	<.001	<.001	3	5
BRCA	NFIL3_S286 →	-0.916	-1.057	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,767 associations by consensus.

Exploration

VAMP2 survival (RNA) · tumor vs normal (RNA) · all VAMP2 data types