UTRN

Across TCGA patient cohorts, UTRN protein abundance is significantly associated with the RNA expression of many other genes, with 18,171 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UTRN-associated genes across cancer lineages are CYBRD1, CNRIP1, and SSPN. Each is linked with UTRN in more than 9 cancer types. Because this analysis shows association rather than direction, both UTRN-to-partner and partner-to-UTRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UTRN versus CYBRD1 in BRCA, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTRN→partner) and Y-score (partner→UTRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CYBRD1 →	+1.511	+0.367	<.001	<.001	3	10
UCEC	CNRIP1 →	+0.957	+0.405	<.001	<.001	3	9
COAD	SSPN →	+0.756	+0.253	<.001	<.001	3	9
UCEC	ABCA8 →	+1.432	+0.452	<.001	<.001	3	9
PDAC	RBMS3 →	+0.862	+0.248	<.001	<.001	3	9
OV	LMOD1 →	+1.408	+0.314	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,171 associations by consensus.

UTRN vs CYBRD1 — BRCA

Explore this scatter interactively →