UTRN

Across TCGA pan-cancer cohorts, UTRN RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of UTRN’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where UTRN RNA is repressed in tumor relative to normal tissue. In most cancer types UTRN is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and LUSC are the cancer types where UTRN tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UTRN RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	−1.583	<.001	9	view →
KICH	Female	All	−2.240	<.001	8	view →
LUSC	Female	II,III,IV	−2.179	<.001	7	view →
BLCA	All	All	−0.761	.004	7	view →
THCA	All	II,III,IV	−0.735	.001	7	view →
BRCA	All	III,IV	−1.348	<.001	6	view →
LIHC	All	All	+0.497	.001	5	view →
CHOL	All	All	+1.951	<.001	4	view →
UCEC	All	All	−1.050	<.001	2	view →
KIRP	Male	All	−0.966	<.001	2	view →
READ	All	All	−0.866	.006	2	view →
PRAD	All	All	+0.845	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

UTRN–LUAD

Open the LUAD breakdown →