UTRN

Across TCGA pan-cancer cohorts, UTRN RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated UTRN data layer compared with 13 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher UTRN RNA is associated with better overall survival. In most high-consensus cancer types, elevated UTRN expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

KIRC, SKCM, and HNSC are the cancer types where UTRN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.716	0.546	<.001	170	view →
SKCM	OS	Median	All	0.843	0.710	<.001	97	view →
HNSC	DFS	Median	All	0.776	0.641	<.001	61	view →
LIHC	OS	Median	All	0.716	0.834	.005	39	view →
UCS	OS	Median	IV	0.732	0.224	.018	36	view →
BRCA	DFS	Quartile	III,IV	0.838	0.629	.002	25	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	24	view →
KICH	DFS	Tertile	II,III,IV	0.497	1.000	<.001	22	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	17	view →
MESO	OS	Quartile	IV	0.122	0.741	.009	14	view →
READ	OS	Median	All	0.901	0.319	.016	14	view →
SARC	DFS	Quartile	All	0.676	0.432	.010	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

UTRN–KIRC (OS)

Open the KIRC breakdown →