UTRN

Across TCGA cell cohorts, UTRN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,784 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UTRN-associated GO terms across cancer lineages are Regulation of transforming growth factor beta receptor signaling pathway, Negative regulation of calcium ion export across plasma membrane, and Positive regulation of cell-matrix adhesion. Each is linked with UTRN in more than 12 cancer types. Because this analysis shows association rather than direction, both UTRN-to-partner and partner-to-UTRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transforming growth factor beta receptor signaling pathway grouped by UTRN-low versus UTRN-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTRN→partner) and Y-score (partner→UTRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of transforming growth factor beta receptor signaling pathway →	+0.062	+1.788	<.001	<.001	3	12
CNS	Negative regulation of calcium ion export across plasma membrane →	+0.079	+1.951	<.001	<.001	3	12
BONE	Positive regulation of cell-matrix adhesion →	+0.171	+1.634	<.001	<.001	3	12
BONE	Vesicle-mediated transport to the plasma membrane →	+0.095	+2.123	<.001	.005	3	12
BONE	Positive regulation of cell-substrate adhesion →	+0.159	+1.192	<.001	.003	3	12
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.151	+2.255	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,784 associations by consensus.

Regulation of transforming growth factor beta receptor signaling pathway by UTRN expression — BREAST

Explore this box plot interactively →