UTP20

Across TCGA patient cohorts, UTP20 mutation is significantly associated with the RNA expression of many other genes, with 6,511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UTP20-associated genes across cancer lineages are TRAIP, MTFP1, and RNASEH2A. Each is linked with UTP20 in more than 5 cancer types. Because this analysis shows association rather than direction, both UTP20-to-partner and partner-to-UTP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAIP grouped by UTP20-low versus UTP20-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP20→partner) and Y-score (partner→UTP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRAIP →	+0.647	+3.596	.001	.001	2	6
UCEC	MTFP1 →	+0.536	+1.643	<.001	<.001	3	5
UCEC	RNASEH2A →	+0.417	+2.233	<.001	<.001	3	5
UCEC	CCDC51 →	+0.390	+1.527	<.001	<.001	3	5
UCEC	COQ2 →	+0.338	+1.212	<.001	<.001	3	5
CESC	GPI →	+0.591	+3.184	.003	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,511 associations by consensus.

TRAIP by UTP20 expression — HNSC

Explore this box plot interactively →