UTP20

Across TCGA pan-cancer cohorts, UTP20 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated UTP20 data layer compared with 10 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher UTP20 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UTP20 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

MESO, LIHC, and KIRC are the cancer types where UTP20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	All	0.233	0.479	<.001	107	view →
LIHC	DFS	Median	All	0.466	0.614	<.001	75	view →
KIRC	OS	Median	All	0.723	0.554	<.001	57	view →
LGG	OS	Median	All	0.732	0.893	<.001	54	view →
UCS	DFS	Tertile	II,III,IV	0.554	0.158	.003	52	view →
BLCA	DFS	Quartile	II,III,IV	0.407	0.578	.003	37	view →
OV	OS	Median	All	0.797	0.881	.003	30	view →
LUSC	DFS	Tertile	III,IV	0.254	1.000	.001	29	view →
ACC	DFS	Tertile	All	0.530	0.818	.002	23	view →
HNSC	OS	Tertile	All	0.582	0.818	.002	19	view →
UCEC	OS	Quartile	III,IV	0.921	0.776	.010	18	view →
KIRP	OS	Median	All	0.588	0.896	.010	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

UTP20–MESO (DFS)

Open the MESO breakdown →