USP9Y

Across TCGA patient cohorts, USP9Y mutation is significantly associated with the RNA expression of many other genes, with 351 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible USP9Y-associated genes across cancer lineages are ZNF736P7Y, RNU6-888P, and RN7SL578P. Each is linked with USP9Y in more than 2 cancer types. Because this analysis shows association rather than direction, both USP9Y-to-partner and partner-to-USP9Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF736P7Y grouped by USP9Y-low versus USP9Y-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP9Y→partner) and Y-score (partner→USP9Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF736P7Y →	+0.045	+5.739	<.001	.001	3	3
BLCA	RNU6-888P →	+0.198	+3.411	<.001	.005	3	2
READ	RN7SL578P →	+0.172	+5.039	<.001	.008	3	2
READ	BPNT2P →	+0.148	+6.681	<.001	<.001	3	2
SKCM	C3orf14 →	+0.639	+3.182	.002	.009	3	2
SKCM	RN7SL762P →	+0.206	+2.439	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 351 associations by consensus.

ZNF736P7Y by USP9Y expression — LUAD

Explore this box plot interactively →