USP9Y

Across TCGA patient cohorts, USP9Y mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible USP9Y-associated genes across cancer lineages are Fibroblasts, Endothelial cells, and Osteoblast. Each is linked with USP9Y in more than 1 cancer types. Because this analysis shows association rather than direction, both USP9Y-to-partner and partner-to-USP9Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by USP9Y-low versus USP9Y-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP9Y→partner) and Y-score (partner→USP9Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Fibroblasts →	+0.013	+5.339	.036	.047	3	1
SKCM	Endothelial cells →	-0.039	-2.974	.041	.035	3	1
SKCM	Osteoblast →	-0.046	-3.453	.013	.005	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Fibroblasts by USP9Y expression — HNSC

Explore this box plot interactively →