USP44

Across TCGA patient cohorts, USP44 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,085 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP44-associated proteins across cancer lineages are XRCC1_S418, XRCC1_S447, and PDE3A_S570. Each is linked with USP44 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP44-to-partner and partner-to-USP44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP44 versus XRCC1_S418 in LUAD, with a Pearson correlation of 1.00.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP44→partner) and Y-score (partner→USP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	XRCC1_S418 →	+1.105	+1.101	<.001	<.001	3	2
BRCA	XRCC1_S447 →	+0.743	+0.714	<.001	<.001	3	2
BRCA	PDE3A_S570 →	+0.958	+1.171	.002	<.001	3	2
BRCA	NOL8_S890 →	+1.150	+0.976	<.001	<.001	3	2
BRCA	IRF2BP1_S384 →	+0.934	+0.742	.001	<.001	3	2
LUAD	IWS1_S363 →	+1.601	+1.423	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,085 associations by consensus.

USP44 vs XRCC1_S418 — LUAD

Explore this scatter interactively →