Q-omics provides the consensus-scored USP27X-AS1 profile across patient tissues and cancer cell-line models. USP27X-AS1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, USP27X-AS1 is differentially expressed in 12, with the highest sampling consensus in THCA. Additionally, USP27X-AS1 RNA expression shows 19,849 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, THCA, and UVM as cancer lineages where USP27X-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for USP27X-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes USP27X-AS1 survival associations across molecular data types. USP27X-AS1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible USP27X-AS1 RNA expression–survival associations across cancer types. High USP27X-AS1 expression shows unfavorable associations in LIHC and LUSC, but favorable associations in KIRC, ACC, MESO and SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for USP27X-AS1 RNA expression.
This table summarizes USP27X-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for USP27X-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. USP27X-AS1 shows lower tumor expression in THCA, LUAD, UCEC and LUSC and higher tumor expression in LIHC and COAD. The THCA box plot shows higher USP27X-AS1 RNA expression in normal versus tumor tissue (log2 FC = −1.450, t-test p < 0.001).
This table shows molecular features associated with USP27X-AS1 in patient tissues and cancer cell lines. In patient samples, USP27X-AS1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
