USP2-AS1

Across TCGA patient cohorts, USP2-AS1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible USP2-AS1-associated genes across cancer lineages are RNU6-6P, RNU6-1155P, and MIR571. Each is linked with USP2-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP2-AS1-to-partner and partner-to-USP2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-6P grouped by USP2-AS1-low versus USP2-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP2-AS1→partner) and Y-score (partner→USP2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-6P →	+0.592	+3.077	.005	.005	3	1
UCEC	RNU6-1155P →	+0.221	+5.475	<.001	.001	3	1
UCEC	MIR571 →	+0.759	+3.795	.005	.002	3	1
UCEC	MIR100 →	+0.262	+4.660	<.001	.003	3	1
UCEC	RNA5SP424 →	+0.273	+3.505	.003	.005	3	1
UCEC	RNU6-1228P →	+0.197	+4.464	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

RNU6-6P by USP2-AS1 expression — UCEC

Explore this box plot interactively →