USP19

Across TCGA patient cohorts, USP19 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,682 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP19-associated proteins across cancer lineages are RBM15B, PDIA4, and PRDX4. Each is linked with USP19 in more than 5 cancer types. Because this analysis shows association rather than direction, both USP19-to-partner and partner-to-USP19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP19 versus RBM15B in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP19→partner) and Y-score (partner→USP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBM15B →	+0.381	+0.824	<.001	<.001	3	6
CCRCC	PDIA4 →	-0.491	-0.243	<.001	.002	3	5
CCRCC	PRDX4 →	-0.506	-0.303	<.001	<.001	3	5
OV	QRICH1 →	+0.289	+0.616	<.001	.003	2	6
GBM	KIAA1143 →	+0.333	+0.230	<.001	<.001	3	5
CCRCC	RRBP1 →	-0.374	-0.287	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,682 associations by consensus.

USP19 vs RBM15B — OV

Explore this scatter interactively →