USHBP1

Across TCGA cell cohorts, USHBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,335 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible USHBP1-associated GO terms across cancer lineages are Regulation of cytoplasmic pattern recognition receptor signaling pathway, Regulation of MDA-5 signaling pathway, and Metaphase/anaphase transition of mitotic cell cycle. Each is linked with USHBP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both USHBP1-to-partner and partner-to-USHBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic pattern recognition receptor signaling pathway grouped by USHBP1-low versus USHBP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USHBP1→partner) and Y-score (partner→USHBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.072	+0.231	<.001	<.001	3	7
CNS	Regulation of MDA-5 signaling pathway →	+0.141	+0.088	<.001	.005	3	6
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.162	+0.162	.004	.001	3	6
BLOOD_Lymphoma	Intermembrane lipid transfer →	+0.050	+0.511	.006	.004	3	5
URINARY_TRACT	Positive regulation of telomerase RNA localization to Cajal body →	+0.058	+0.135	.002	.002	3	5
BONE	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.125	+0.111	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,335 associations by consensus.

Regulation of cytoplasmic pattern recognition receptor signaling pathway by USHBP1 expression — BONE

Explore this box plot interactively →