USHBP1

Across TCGA cell cohorts, USHBP1 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USHBP1-associated genes across cancer lineages are BRDT, OR2T6, and SLC32A1. Each is linked with USHBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both USHBP1-to-partner and partner-to-USHBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRDT grouped by USHBP1-low versus USHBP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USHBP1→partner) and Y-score (partner→USHBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BRDT →	+0.159	+4.342	<.001	.002	3	2
SOFT_TISSUE	OR2T6 →	+0.012	+4.930	<.001	.008	3	1
BLOOD_Leukemia	SLC32A1 →	+0.946	+3.901	<.001	.006	3	1
BLOOD_Leukemia	HCN4 →	+0.037	+3.855	.002	.007	3	1
BLOOD_Leukemia	AWAT2 →	+0.012	+3.705	<.001	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.122	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

BRDT by USHBP1 expression — BLOOD_Leukemia

Explore this box plot interactively →