UQCRQ

Across TCGA cell cohorts, UQCRQ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,739 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible UQCRQ-associated GO terms across cancer lineages are Dihydrofolate metabolic process, Mitochondrial respiratory chain complex assembly, and [2Fe-2S] cluster assembly. Each is linked with UQCRQ in more than 12 cancer types. Because this analysis shows association rather than direction, both UQCRQ-to-partner and partner-to-UQCRQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by UQCRQ-low versus UQCRQ-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRQ→partner) and Y-score (partner→UQCRQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Dihydrofolate metabolic process →	+0.225	+1.187	<.001	<.001	3	13
BREAST	Mitochondrial respiratory chain complex assembly →	+0.068	+0.899	.002	<.001	3	11
BREAST	[2Fe-2S] cluster assembly →	+0.114	+0.756	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial translation →	+0.084	+0.879	<.001	<.001	3	10
BLOOD_Myeloma	Protein import into mitochondrial intermembrane space →	+0.143	+0.928	.008	.009	3	10
BONE	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	-0.056	-0.716	.009	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,739 associations by consensus.

Dihydrofolate metabolic process by UQCRQ expression — URINARY_TRACT

Explore this box plot interactively →