UQCRQ

Across TCGA pan-cancer cohorts, UQCRQ RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of UQCRQ’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where UQCRQ RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UQCRQ is over-expressed in tumor, although a few such as HNSC and STAD show the opposite, repressed pattern.

LIHC, LUAD, and HNSC are the cancer types where UQCRQ tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UQCRQ RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.746	<.001	8	view →
LUAD	Female	All	+0.583	<.001	7	view →
HNSC	All	All	−0.335	<.001	7	view →
UCEC	All	III,IV	+1.062	<.001	6	view →
BRCA	All	III,IV	+0.939	<.001	6	view →
KIRC	Female	IV	+0.665	.008	4	view →
COAD	Female	II,III,IV	+0.492	.005	4	view →
STAD	Male	All	−0.441	.008	2	view →
LUSC	All	All	+0.193	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

UQCRQ–LIHC

Open the LIHC breakdown →